{"id":278941,"date":"2025-09-03T17:06:42","date_gmt":"2025-09-03T22:06:42","guid":{"rendered":"https:\/\/dallasinnovates.com\/?p=278941"},"modified":"2025-09-03T17:19:36","modified_gmt":"2025-09-03T22:19:36","slug":"nih-taps-ut-southwestern-for-north-texas-alzheimers-disease-research-hub-bringing-ai-and-digital-twins-to-the-fight","status":"publish","type":"post","link":"https:\/\/dallasinnovates.com\/nih-taps-ut-southwestern-for-north-texas-alzheimers-disease-research-hub-bringing-ai-and-digital-twins-to-the-fight\/","title":{"rendered":"NIH Taps UT Southwestern Medical Center for $23M North Texas Alzheimer’s Disease Research Hub"},"content":{"rendered":"

North Texas is the newest federal front line in the fight against Alzheimer’s and dementia.<\/strong><\/p>\n

The National Institute of Health has awarded UT Southwestern a $23 million, five-year grant from the National Institute on Aging to establish the North Texas Alzheimer’s Disease Research Center (ADRC). The designation makes it one of 37 such centers nationwide and the second in Texas, according to an announcement.<\/p>\n

The new center, based at UT Southwestern Medical Center, will be a focal point for research that could reset how the disease is detected and treated. Scientists plan to probe how cardiometabolic conditions like high blood pressure accelerate dementia, train AI to hear vocal cues of cognitive decline, and build digital replicas of patients to test therapies.<\/p>\n

Texas by the numbers<\/h3>\n

Texas, which is the nation’s second most populous state, has the third-highest number of Alzheimer’s patients, the second-highest Alzheimer’s-related deaths, and the highest dementia burden score, according to UTSW. The dementia burden score is a measure of the emotional and psychological toll on caregivers. <\/p>\n

That reality, paired with UT Southwestern’s long-standing strength in neurology and its Peter O’Donnell Jr. Brain Institute, laid the groundwork for the designation.<\/p>\n

Tackling cardiometabolic factors in dementia and more<\/h3>\n

Each Alzheimer’s Disease Research Center operates with a unique theme. In North Texas, the focus will be on advancing the national agenda by exploring how cardiometabolic factors, especially hypertension, contribute to Alzheimer’s and related dementias. Hypertension affects nearly 120 million Americans, according to UTSW.<\/p>\n

The center also plans to use AI voice analysis to discover vocal changes that accompany cognitive decline. Researchers will develop “digital twin” technology to create virtual representations of patients, which will help distinguish between factors associated with normal aging and those linked to dementias, according to Dr. Ihab Hajjar, principal investigator of the new center.<\/p>\n

“Being named an ADRC is not only an indication of scientific excellence, but also highlights an intentional commitment to research Alzheimer’s disease and cognitive impairment in our community,” said Hajjar, who is professor of neurology and internal medicine at UT Southwestern, in a statement.<\/p>\n

Hajjar said the designation gives North Texas “the chance to make an unprecedented leap in understanding and treating Alzheimer’s disease and related dementias.”<\/p>\n

\"\"

Dr. Ihab Haijar [Photo: UT Southwestern Medical Center]<\/p><\/div>\n

North Texas collaboration in the dementia fight<\/h3>\n

The designation is designed in collaboration with UT Dallas and UT Arlington. <\/p>\n

The North Texas ADRC will not only enable new science but also “enhance scientific and clinical collaborations locally and nationally” while creating education opportunities for researchers, clinicians, and learners,\u00a0according to UTSW.\u00a0<\/p>\n

Dr. William T. Dauer, director of the Peter O’Donnell Jr. Brain Institute, points to the new designation as proof of what can happen when institutions combine their strengths.<\/p>\n

“This designation reflects the power of bringing together outstanding scientists, clinicians, and community partners to tackle one of the most urgent societal challenges,” Dauer said in the announcement. “It will strengthen our ability to link discoveries from O’Donnell Brain Institute laboratories with the needs of patients and families in North Texas and beyond, accelerating progress against Alzheimer’s disease and related dementias.”<\/p>\n

Dr. Elan D. Louis, chair and professor of neurology and an investigator in the O’Donnell Brain Institute, noted that the ADRC reflects momentum already underway across his department.<\/p>\n

“Our new ADRC reflects a growing emphasis in the Department of Neurology on learning about, understanding, and treating a group of disorders that affect millions of elderly people nationwide,” Louis said.<\/p>\n

Feeding a national data engine for dementia research\u00a0<\/h3>\n

The research generated by all ADRCs will feed into communal datasets that are made publicly available to spur collaboration and speed discovery. Hajjar said those shared efforts could offer “hope to patients with dementia and their loved ones.”<\/p>\n

Dementia research is a core area within UTSW, and the new center builds on a decade of work by the O’Donnell Brain Institute.<\/p>\n

UTSW also notes its No. 9 ranking for Neurology & Neurosurgery on U.S. News & World Report’s Best Hospitals list and 12 nationally ranked specialties, the most of any hospital in Texas. To date, its faculty have received six Nobel Prizes and include 24 members of the National Academy of Sciences, 23 members of the National Academy of Medicine, and 13 Howard Hughes Medical Institute Investigators.<\/p>\n

Leadership brings specialized expertise<\/h3>\n

UTSW said the center’s leadership team brings long-standing expertise in neurological research with distinct but complementary focuses.\u00a0 Dr. Dauer holds the Lois C.A. and Darwin E. Smith Distinguished Chair in Neurological Mobility Research. Dr. Hajjar holds the Pogue Family Distinguished University Chair in Alzheimer’s Disease Clinical Research and Care, in Memory of Maurine and David Weigers McMullan. Dr. Louis holds the Linda and Mitch Hart Distinguished Chair in Neurology.<\/p>\n

The ADRCs were established in 1984 as congressionally designated NIH Centers of Excellence. The mission includes improving detection, diagnosis, treatment, prevention, and care for patients and families. Each center tailors its theme to local populations and scientific priorities.<\/p>\n

The North Texas center joins another Texas ADRC, a collaboration between UT Health San Antonio and The University of Texas Rio Grande Valley designated in 2021, strengthening the state’s role in national dementia research efforts.<\/p>\n

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 <\/p>\n","protected":false},"excerpt":{"rendered":"

The new federal Alzheimer’s hub joins an elite network of 37 centers nationwide. Scientists from UT Southwestern, UT Arlington, and UT Dallas will decode dementia by exploring hypertension’s role, analyzing voice patterns with AI, and creating virtual patient models.<\/p>\n","protected":false},"author":8,"featured_media":278962,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[8,201981,9,12],"tags":[206687,6630,9377,206686,206688,2087,21406,206685,122522,206683,8808,179265,175308,4689,4939,853,5327,244,243,993,206684],"class_list":["post-278941","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-enterprise","category-discovery","category-education","category-invention","tag-adrc","tag-ai","tag-alzheimers-disease","tag-alzheimers-disease-research-centers","tag-cardiometabolic-health","tag-dementia","tag-digital-twins","tag-elan-d-louis","tag-hypertension","tag-ihab-hajjar","tag-machine-learning","tag-national-institute-on-aging","tag-neurology","tag-neuroscience","tag-nih","tag-north-texas","tag-peter-odonnell-jr-brain-institute","tag-ut-arlington","tag-ut-dallas","tag-ut-southwestern","tag-william-t-dauer"],"acf":[],"yoast_head":"\nNIH 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Preston launched the Dallas Innovates' media platform to tell the story of innovation in Dallas-Fort Worth. It was official in 2016 when the Dallas skyline turned purple for innovation. Since then, Dallas Innovates has become a must-read among business leaders and forward thinkers in North Texas. \\\"Our partners call us 'the tip of the spear for innovation news in North Texas,'\\\" she says. \\\"Now it's our tagline.\\\" The media-with-a-mission brand covers what's new and next in North Texas business. \\\"Our lens is lift,\\\" Preston says. \\\"We want to inspire ideas and opportunity. We're a catalyst for connections, here and beyond.\\\" Covering the Dallas-Fort Worth Innovation Economy \\\"Dallas-Fort Worth has all of the core assets that drive an innovation economy,\\\" Preston told D CEO about the launch. \\\"We felt Dallas Innovates could be the center of innovation in business in DFW, from startup to enterprise, and include all the great impact work happening here.\\\" One of our superpowers is our diverse economy: \\\"A lot of places want one thing to hang their hat on, but DFW has many centers of innovation,\\\" she noted. \\\"And the fact that small businesses can work with very large companies here as a Fortune 50 market is a huge advantage.\\\" Preston founded media company Dallas Next in 2021 and publishes Dallas Innovates in a collaboration with the Dallas Regional Chamber. DRC innovation and research chief Duane Dankesreiter and Dallas Innovates co-founder says it's \\\"the drumbeat\\\" for the innovation economy in the region. Dallas Next also publishes the DALLAS\u00ae publications in partnership with the DRC. Dallas Innovates' sister publications include the DALLAS\u00ae Regional Economic Development Guide, the DALLAS\u00ae Relocation + Newcomers Guide, and the\u00a0DALLAS\u00ae Commercial Real Estate, which is a partnership with the DRC and The Real Estate Council. \\\"It's hard to say no to Quincy Preston when she believes in something,\\\" wrote D CEO Editor Christine Perez in the magazine. \\\"She won't stop until she makes it happen.\\\" In a previous role at D Magazine Partners, Preston incubated Dallas Innovates and published the DRC's brand publications. There, she also led the launch of D Healthcare Daily at D CEO and the launch of D TV. Preston developed data solutions to provide insights and measurement for growth across D Magazine Partners brands. Preston has worn many hats in her media career, including stints as a writer, photographer, and award-winning designer. During her long tenure at the Dallas Business Journal, Preston managed budgets, project schedules, resources, and talent; she also developed several cost-saving and income-producing initiatives that were adopted across the ACBJ chain of more than 40 newspapers. Preston's first editorial job was working for a fashion magazine at the Dallas Apparel Mart with an office a few doors down from Lucy Billingsley, daughter of legendary real estate developer Trammell Crow. At the time, Billingsley was running the market center where she led three expansions and a ~7 million-square-foot development. It was good company to be in. Later, when Preston launched an agency that she ran through the early nineties, Billingsley helped her with tough-but-kind advice\u2014and some pivotal connections. Today, Preston helms Dallas Innovates and the DALLAS\u00ae publications group, published by Dallas Next for the Dallas Regional Chamber. The growing DALLAS\u00ae platform includes sister publication Dallas Innovates. Together they focus on Dallas-Fort Worth business, including real estate, relocation, economic development, and innovation. 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Preston launched the Dallas Innovates' media platform to tell the story of innovation in Dallas-Fort Worth. It was official in 2016 when the Dallas skyline turned purple for innovation. Since then, Dallas Innovates has become a must-read among business leaders and forward thinkers in North Texas. \"Our partners call us 'the tip of the spear for innovation news in North Texas,'\" she says. \"Now it's our tagline.\" The media-with-a-mission brand covers what's new and next in North Texas business. \"Our lens is lift,\" Preston says. \"We want to inspire ideas and opportunity. We're a catalyst for connections, here and beyond.\" Covering the Dallas-Fort Worth Innovation Economy \"Dallas-Fort Worth has all of the core assets that drive an innovation economy,\" Preston told D CEO about the launch. \"We felt Dallas Innovates could be the center of innovation in business in DFW, from startup to enterprise, and include all the great impact work happening here.\" One of our superpowers is our diverse economy: \"A lot of places want one thing to hang their hat on, but DFW has many centers of innovation,\" she noted. \"And the fact that small businesses can work with very large companies here as a Fortune 50 market is a huge advantage.\" Preston founded media company Dallas Next in 2021 and publishes Dallas Innovates in a collaboration with the Dallas Regional Chamber. DRC innovation and research chief Duane Dankesreiter and Dallas Innovates co-founder says it's \"the drumbeat\" for the innovation economy in the region. Dallas Next also publishes the DALLAS\u00ae publications in partnership with the DRC. Dallas Innovates' sister publications include the DALLAS\u00ae Regional Economic Development Guide, the DALLAS\u00ae Relocation + Newcomers Guide, and the\u00a0DALLAS\u00ae Commercial Real Estate, which is a partnership with the DRC and The Real Estate Council. \"It's hard to say no to Quincy Preston when she believes in something,\" wrote D CEO Editor Christine Perez in the magazine. \"She won't stop until she makes it happen.\" In a previous role at D Magazine Partners, Preston incubated Dallas Innovates and published the DRC's brand publications. There, she also led the launch of D Healthcare Daily at D CEO and the launch of D TV. Preston developed data solutions to provide insights and measurement for growth across D Magazine Partners brands. Preston has worn many hats in her media career, including stints as a writer, photographer, and award-winning designer. During her long tenure at the Dallas Business Journal, Preston managed budgets, project schedules, resources, and talent; she also developed several cost-saving and income-producing initiatives that were adopted across the ACBJ chain of more than 40 newspapers. Preston's first editorial job was working for a fashion magazine at the Dallas Apparel Mart with an office a few doors down from Lucy Billingsley, daughter of legendary real estate developer Trammell Crow. At the time, Billingsley was running the market center where she led three expansions and a ~7 million-square-foot development. It was good company to be in. Later, when Preston launched an agency that she ran through the early nineties, Billingsley helped her with tough-but-kind advice\u2014and some pivotal connections. Today, Preston helms Dallas Innovates and the DALLAS\u00ae publications group, published by Dallas Next for the Dallas Regional Chamber. The growing DALLAS\u00ae platform includes sister publication Dallas Innovates. Together they focus on Dallas-Fort Worth business, including real estate, relocation, economic development, and innovation. Connect on social media: LinkedIn, Twitter\u00a0 Send news and tips here.","sameAs":["http:\/\/www.dallasinnovates.com","https:\/\/x.com\/quincypreston"],"url":"https:\/\/dallasinnovates.com\/author\/quincy-preston\/"}]}},"_links":{"self":[{"href":"https:\/\/dallasinnovates.com\/wp-json\/wp\/v2\/posts\/278941","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dallasinnovates.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dallasinnovates.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dallasinnovates.com\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/dallasinnovates.com\/wp-json\/wp\/v2\/comments?post=278941"}],"version-history":[{"count":0,"href":"https:\/\/dallasinnovates.com\/wp-json\/wp\/v2\/posts\/278941\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dallasinnovates.com\/wp-json\/wp\/v2\/media\/278962"}],"wp:attachment":[{"href":"https:\/\/dallasinnovates.com\/wp-json\/wp\/v2\/media?parent=278941"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dallasinnovates.com\/wp-json\/wp\/v2\/categories?post=278941"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dallasinnovates.com\/wp-json\/wp\/v2\/tags?post=278941"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}